A human interactome to prioritize drug discovery. Credit: Karen Arnott/EMBL-EBI Scientists at Open Targets, the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), and GSK…
Posts published in “Bioinformatics”
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The research team reconstructed an ancestral enzyme by searching databases for corresponding modern enzymes, using the obtained sequences to calculate the original sequence, and introducing…
Researchers have demonstrated the efficiency of T-cell immune response against the Omicron variant of SARS-CoV-2. In approximately 90% of vaccinated Europeans, T-cell immunity was as…
UC San Diego researchers introduce Multi-Scale Integrated Cell (MuSIC), a technique that combines microscopy, biochemistry and artificial intelligence, revealing previously unknown cell components that may…
Archaic sequence length decay (black bands on chromosomes) for different populations sampled at multiple time points. The length of generation intervals (GI) is represented by…
How do you study a group of organisms with over 300,000 species, dispersed across all seven continents, and with up to 50 times as much…
Protein structures to represent the data obtained via AlphaFold. Credit: Karen Arnott/EMBL-EBI DeepMind and EMBL release the most complete database of predicted 3D structures of…
You’re as old as your immune system. Investigators at the Stanford University School of Medicine and the Buck Institute for Research on Aging have built…
Research by Gustavo Caetano-Anollés and Fayez Aziz, University of Illinois, reveals a “big bang” during evolution of protein subunits known as domains. The team looked…
As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who…
An international study has discovered a coronavirus epidemic broke out in the East Asia region more than 20,000 years ago, with traces of the outbreak…
It has recently become prominent in Mexico and, similarly to other variants, presents a mutation in the Spike protein of the coronavirus. The “Mexican variant”…
This image shows specialized lung cells (resembling a beaded necklace) that may mount a cytokine storm in response to some viral infections. Credit: UC San…
New DNA sequencing technologies and assembly methods let researchers read the entire genomes of 25 species: pale spear-nosed bat, greater horseshoe bat, Egyptian fruit bat,…
The observation that most of the viruses that cause human disease come from other animals has led some researchers to attempt “zoonotic risk prediction” to…
Behold, the gar’s brain. In this microscope image, the brain’s left hemisphere fluoresces green and the right glows magenta. Yet, at the bottom of the…
An interdisciplinary team led by KU Leuven and Stanford has identified 76 overlapping genetic locations that shape both our face and our brain. What the…
Modern hospitals and antibiotic treatment alone did not create all the antibiotic resistant strains of bacteria we see today. Instead, selection pressures from before widespread…
Structure of Genome. Credit: NIH 64 Human Genomes Sequenced Will Serve as New Reference for Genetic Variation and Predisposition to Human Diseases Researchers at the…
Sahas Barve, a Peter Buck Fellow at the Smithsonian’s National Museum of Natural History, led a new study to examine feathers across 249 species of…