Using the novel algorithm FLSHclust, researchers have identified 188 rare and previously unknown CRISPR-linked gene modules, including a groundbreaking type VII CRISPR-Cas system. This discovery,…
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A new molecule, ABBV-CLS-484, developed by TIDE, AbbVie, and Calico Life Sciences, offers a unique dual-action approach against cancer by enhancing tumor susceptibility and boosting…
Microscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism…
Researchers from MIT have created a comprehensive atlas of the types of cells found in the brain cerebrovasculature. Credit: iStockphoto, edited by MIT News Single-cell…
A CRISPR-based gene editing technique called twin prime editing could be a new and safer approach to gene therapy. Researchers at the Broad Institute of…
Credit: Susanna Hamilton, Broad Communications Researchers have boosted the efficiency of prime editing, a highly versatile CRISPR-based gene editing technology, and used the improved system…
Fully assembled SEND packages are released from the cell to be collected for gene therapy. Credit: McGovern Institute Made of components found in the human…
This scanning electron microscope image shows SARS-CoV-2 (round gold particles) emerging from the surface of a cell cultured in the lab. Image captured and colorized…
MIT biological engineers have demonstrated a way to easily retrieve data files stored as DNA. This could be a step toward using DNA archives to…
Single-cell analysis of autopsy samples from COVID-19 patients shows how the lungs repeatedly tried, and failed, to repair themselves. Scientists from several hospitals and research…
In a study of E. coli, MIT researchers discovered that mutations to genes involved in metabolism can also help bacteria to evade the toxic effects…
A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals…
This scanning electron microscope image shows SARS-CoV-2 (round gold objects) emerging from the surface of cells cultured in the lab. Credit: NIAID-RML A CRISPR-based test…
MIT researchers have collected and preserved samples of nearly 8,000 strains of bacteria found in the human digestive tract. Credit: Chelsea Turner, MIT Researchers identify…