Knocking out transposon promoter leads to pup death in mice; similar promoters found in many mammals. Nearly half of our DNADNA, or deoxyribonucleic acid, is…
Posts published in “Developmental Biology”
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The mouse atrioventricular (AV) node. Green staining indicates AV node cells, while red staining highlights neighboring atrial muscle cells. All cell nuclei are stained blue.…
A developing mouse neural tube. Hedgehog signaling is required to produce different types of neuronal progenitor cells, indicated by the different colors. THC inhibits Hedgehog…
A human embryo in the lab at 9 days after fertilization. The hypoblast (a group of cells outside the main embryo) sends a message to…
Like a bonsai, neurons called mitral cells also grow multiple branches. In the beginning, mitral cells branch into many glomeruli, but as development progresses, a…
Tsetse fly giving birth. Credit: Daniel Hargrove The female tsetse fly, which gives birth to adult-sized live young, produce weaker offspring as they get older,…
CLSY3 (fused with a yellow fluorescent protein) is specifically expressed in the tapetal cells surrounding the germ cells. Credit: John Innes Centre Hereditary information is…
This image shows adult coelacanth scales. Credit: Laurent Ballesta Coelacanths may live five times longer than researchers expected. Once thought to be extinct, lobe-finned coelacanths…
In polymicrogyria, the cortex of the brain has many irregular, small folds (gyria) and disorganization of its layers, caused by mutations in one of several…
In Alg mutant embryos, rod cells are initially born but not maintained and undergo programmed cell death indicated in magenta (TUNEL staining). Credit: Clara Becker…
This image shows frog embryos in eggs. Credit: Nicolas Mathevon It’s well known that reptiles depend on temperature cues while in the egg to determine…
In a paper published today in Nature Communications, an international group of collaborators led by researchers at UPMC Children’s Hospital of Pittsburgh have identified a…
This image shows a chimera human-monkey blastocyst. Credit: Weizhi Ji, Kunming University of Science and Technology Investigators in China and the United States have injected…
Professor Jose Polo in front of images of the iBlastoids. Credit: Monash University For first time, fibroblast-derived model of early embryo will allow extensive study…
You’ve heard of animals that can lose and then regenerate a tail or limb. But scientists reporting in the journal Current Biology on March 8 have now…
Immunofluorescence analysis of a group of proliferating stem cells associated with a muscle fiber (grey). The stem cells produce Dll1 (red) and MyoD (green). Two…
The banyan tree Ficus macrocarpa produces aerial roots that give it its distinctive look. A new study reveals the genomic changes that allow the tree…
Neuronal fibers in a healthy brain (top) and a brain with agenesis of the corpus callosum (bottom). In the healthy brain, the two hemispheres are…
Flame retardants in the home are nearly impossible to avoid, and transfer from mothers to offspring in mice. Mice develop diabetes after exposure through mothers.…
This photo shows a young female gelada grooming the dominant breeding male of her group. Credit: Rachel Perlman Most mammals — including humans and other…