Scientists have identified a mutation that significantly boosts the cancer-fighting ability of engineered T cells without causing toxicity. This innovative approach, which works against multiple…
Posts published in “Immunotherapy”
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Scientists have discovered that mutations in mitochondrial DNA can predict a patient’s response to immunotherapy, potentially leading to more personalized and effective cancer treatments. Credit:…
A study by Kyoto and Yokohama City University researchers reveals that the absence of B4GALT3 in mice leads to reduced tumor growth, highlighting potential new…
A new molecule, ABBV-CLS-484, developed by TIDE, AbbVie, and Calico Life Sciences, offers a unique dual-action approach against cancer by enhancing tumor susceptibility and boosting…
A team has discovered a method to enhance the effectiveness of CAR-T cell immunotherapy by inhibiting a metabolic mechanism, thus prolonging the cells’ ability to…
A colorized scanning electron micrograph depicts a single human oral squamous carcinoma cell, the most common form of head and neck cancer. Credit: Wellcome Collection…
An experimental mRNA vaccine, mRNA-4157/V940, combined with immunotherapy pembrolizumab, decreased the likelihood of melanoma recurrence or death by 44% compared to immunotherapy alone in a…
The figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (white) as a chess…
Peanut allergies are a common type of food allergy that affects millions of people worldwide. They are caused by an immune system reaction to proteins…
Breast cancer is a type of cancer that develops in the breast tissue. It is one of the most common types of cancer among women…
Cancer is a disease in which abnormal cells divide and grow in an uncontrolled way. These abnormal cells can form tumors and can spread to…
The new research focused on the failure of a process known as “mismatch repair.” A Yale University study presents a new explanation for why immunotherapy…
Image at left shows the tumor-cell protein PVR binding with the NK-cell receptor KIR2DL5 to prevent NK-cell attack. In image at right, monoclonal antibody short-circuits…
The illustration shows a cancer cell (center) surrounded by immune T-cells augmented with an oncolytic (cancer-fighting) virus. A new study describes how a combination of…
Researchers identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat…
A type of T cell known as CD4-positive helper T cells was identified by researchers. These T cells contributed to the development of a series…
Killer-T cells (green) attack lymphatic vessels (red) in tumors and induce their death (cell death marker in white). Credit: UNIGE – Robert Pick / Stéphanie…
Study shows combined IL-6 and immune checkpoint blockade reduces toxicity while preserving anti-tumor immune response The University of Texas MD Anderson Cancer Center researchers have…
Glioma cells. Credit: University of Michigan Rogel Cancer Center The approach, studied in mice, overcomes the blood-brain barrier and breaks the shield tumors build against…
HKUMed develops a novel therapeutic approach against nasopharyngeal carcinoma by using exosomes derived from γδ-T cells synergized with radiotherapy A research team at LKS Faculty…