University of Cincinnati researcher urges caution using remdesivir to treat COVID-19. While the world has its eyes on vaccines to stop the spread of coronavirus,…
Posts published in “Pharmaceuticals”
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Graphic illustration of the work: DNA-programmed affinity labeling (DPAL) enables the direct screening of DNA-encoded chemical libraries (DELs) against membrane protein targets on live cells…
An orange-red dye shows that blood clots formed in a mouse ear in which thrombin was released from light-triggered RBCs. Scale bar, 50 μm. Credit:…
Purdue University scientists are using machine learning models to create new options for drug discovery pipelines. Credit: Purdue University/Gaurav Chopra One-step multicomponent reaction with interpretable…
The Gram-negative cell envelope and pathways of drug fluxes across it. Credit: Zhao, S., Adamiak, J.W., Bonifay, V. et al. Defining new chemical space for…
A systematic review of published research found that financial payments from the drug industry to U.S. physicians was associated with increased prescribing of the paying…
In thiol-mediated uptake, dynamic covalent exchange with thiols on the cell surface precedes entry through different mechanisms. Inhibition of thiol-mediated uptake by removal of exofacial…
Monoclonal antibody tested at University of São Paulo and experimental drug given to patients in Italy by University of Pennsylvania research group promoted rapid improvement…
A discovery by UVA researchers Dorian A. Rosen and Alban Gaultier led to a recent clinical trial that found that an antidepressant may stop COVID…
Immuneering develops drugs to bind to disease pathways and silence them. Credit: Immuneering Immuneering uses bioinformatics to develop new medicines while also helping large pharmaceutical…
University of Pittsburgh School of Medicine scientists have discovered the fastest way to identify potent, neutralizing human monoclonal antibodies against SARS-CoV-2, the virus that causes…
Proposed structure of Bi-bound zinc-binding domain of SARS-CoV-2 helicase. Through kicking out the crucial zinc(II) ions in the zinc-binding domain of SARS-CoV-2 helicase, RBC demonstrated…
A public health advisory issued by the US Food and Drug Administration (FDA) in 2003, followed by drug label warnings, indicated that children and adolescents…
A picture of a planaria flatworm under a microscope that has been treated with a known skin irritant mixed with a fluorescent dye. Credit: University…
As the antimalarial drugs hydroxychloroquine and chloroquine have drawn attention as potential therapies for COVID-19 and are being widely used off-label, it’s now more important…
Short-term hydroxychloroquine treatment is not associated with lethal heart rhythms in patients with COVID-19 who are risk assessed prior to receiving the drug. That’s the…
Wei Li, Ph.D., of Pitt, demonstrates a step in the process of obtaining a potential drug against COVID-19. Credit: UPMC University of Pittsburgh School of…
In study, acetaminophen alters perceptions of risk. While acetaminophen is helping you deal with your headache, it may also be making you more willing to…
Cannabidiol (CBD) is an increasingly popular wellness trend. The compound, which occurs naturally in cannabis plants, is added to many products that claim to reduce…
The stylized yeast cells depicted in several leaves and flower petals are an artist’s interpretation of how scientists, using the tools of synthetic biology, genetically…