“We think the kind of reactions we’ve described are probably what could have happened on early Earth,” says Ramanarayanan Krishnamurthy. The reaction generates the building…
Posts published in “Scripps Research Institute”
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This HYBRiD visualization of a whole mouse chest after SARS-CoV-2 infection shows the viral protein in red and tissue structures (lung, blood vessel, bone) in…
A team at Scripps Research reveals details into how Parkinson’s disease and Lewy body dementia spread in the brain. In neurons, the LC3 protein (green)…
Neurons grown in culture expressing a mutant prion protein (cyan) that cause prion disease in humans. These neurons display swollen axons that contain toxic mutant…
Scientists working in the lab of Ben Shen, PhD, at Scripps Research, Florida have found a new family of sulfur-installing enzymes by mining the genomes…
Scientists at Scripps Research find evidence that antibody treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response that erodes their positive effects.…
Newly described chemical reaction could have assembled DNA building blocks before life forms and their enzymes existed. Discovery boosts theory that life on our planet…
Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine. Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in…
Many flu strains may be capable of mutating to escape universal-vaccine antibodies. Some common strains of influenza have the potential to mutate to evade broad-acting…

“Silent” Carriers: Extraordinary Percentage of SARS-CoV-2 Coronavirus Infections May Be Asymptomatic
Analysis of data from 16 groups of COVID-19 patients suggest ‘silent’ carriers may exacerbate efforts to stop spread of the disease. An extraordinary percentage of…
Billiard-like break shot to cell-membrane structures triggers brain’s loss of consciousness from anesthesia, scientists find. Surgery would be inconceivable without general anesthesia, so it may…
IBM’s World Community Grid hosts Scripps Research project to virtually screen chemical compounds that might help fight COVID-19. Under a collaboration between IBM and Scripps…

No Evidence COVID-19 Coronavirus Was Genetically Engineered in a Lab – Epidemic Has a Natural Origin
Electron microscopy photo of the COVID-19 coronavirus. Scripps Research’s analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the…
An unexpected approach blurs the line between synthetic drug molecules and natural products, with the goal of achieving higher quality compounds for medicines. In a…
Compounds called cyclophospholipids would have held up against the planet’s harsh conditions, helping the first cells form and proliferate. To truly understand how the body…
Using C. elegans, Scripps Research neuroscientists Brock Grill, Kirill Martemyanov and Dandan Wang discovered a new genetic regulator of opioid signalling. Credit: Scott Wiseman for…