Detailed structural imagery of public bnAbs and where they bind to SARS-CoV-2 (green helix) and MERS-CoV (orange helix). These bnAbs recognize the S2 region of…
Posts published in “Scripps Research Institute”
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Researchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-dependent mice.…
A study by Scripps Research and eMed digital medicine shows a surprisingly high percentage of COVID-19 rebound cases in both untreated individuals and those treated…
Apremilast is a medication used for the treatment of psoriatic arthritis, psoriasis, and ankylosing spondylitis. It works by blocking the activity of an enzyme called…
Otezla® is a prescription medicine used to treat moderate to severe plaque psoriasis in adults. It works by inhibiting an enzyme called phosphodiesterase 4 (PDE4),…
Researchers at Scripps Research have created a novel instrument to monitor brain plasticity. Researchers at Scripps Research examined how the levels of various proteins in…
The researchers believe that the compound will be effective even for new variants. The Scripps Research team demonstrated that a variant of an existing FDA-approved…
“We think the kind of reactions we’ve described are probably what could have happened on early Earth,” says Ramanarayanan Krishnamurthy. The reaction generates the building…
This HYBRiD visualization of a whole mouse chest after SARS-CoV-2 infection shows the viral protein in red and tissue structures (lung, blood vessel, bone) in…
A team at Scripps Research reveals details into how Parkinson’s disease and Lewy body dementia spread in the brain. In neurons, the LC3 protein (green)…
Neurons grown in culture expressing a mutant prion protein (cyan) that cause prion disease in humans. These neurons display swollen axons that contain toxic mutant…
Scientists working in the lab of Ben Shen, PhD, at Scripps Research, Florida have found a new family of sulfur-installing enzymes by mining the genomes…
Scientists at Scripps Research find evidence that antibody treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response that erodes their positive effects.…
Newly described chemical reaction could have assembled DNA building blocks before life forms and their enzymes existed. Discovery boosts theory that life on our planet…
Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine. Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in…
Many flu strains may be capable of mutating to escape universal-vaccine antibodies. Some common strains of influenza have the potential to mutate to evade broad-acting…
“Silent” Carriers: Extraordinary Percentage of SARS-CoV-2 Coronavirus Infections May Be Asymptomatic
Analysis of data from 16 groups of COVID-19 patients suggest ‘silent’ carriers may exacerbate efforts to stop spread of the disease. An extraordinary percentage of…
Billiard-like break shot to cell-membrane structures triggers brain’s loss of consciousness from anesthesia, scientists find. Surgery would be inconceivable without general anesthesia, so it may…
IBM’s World Community Grid hosts Scripps Research project to virtually screen chemical compounds that might help fight COVID-19. Under a collaboration between IBM and Scripps…