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Groundbreaking Discovery of “Special” Muscle That Can Promote Fat Burning While Sitting

“Special” muscle can promote glucose and fat burning to fuel metabolism for hours while sitting.

The ‘Soleus Pushup’ is a metabolic innovation that rivals any therapeutic approach.

A groundbreaking discovery from the same mind whose research propelled the notion that “sitting too much is not the same as exercising too little” is set to turn a sedentary lifestyle on its ear: Though only 1% of your body weight, the soleus muscle in the calf, if activated correctly, can do big things to significantly enhance the metabolic health in the rest of your body.

And Marc Hamilton, professor of Health and Human Performance at the University of Houston (UH), has discovered such an approach for optimal activation. He is pioneering the “soleus pushup” (SPU) which effectively elevates muscle metabolism for hours, even while sitting. One of 600 muscles in the human body, the soleus is a posterior lower leg muscle that runs from just below the knee to the heel.

“We are unaware of any existing or promising pharmaceuticals that come close to raising and sustaining whole-body oxidative metabolism at this magnitude.” — Marc Hamilton

Published recently in the journal iScience, Hamilton’s research indicates that the soleus pushup’s ability to sustain an elevated oxidative metabolism to improve the regulation of blood glucose is more effective than any popular methods currently touted as a solution. For example, the soleus pushup is more effective at elevating oxidative metabolism than exercise, weight loss, and intermittent fasting. Oxidative metabolism is the process by which oxygen is used to burn metabolites like blood glucose or fats. However, it depends, in part, on the immediate energy needs of the muscle when it’s working.

The soleus pushup activates the soleus muscle differently than when standing or walking. Credit: University of Houston

When the SPU was tested, the whole-body effects on blood chemistry included a 52% improvement in the excursion of blood glucose (sugar) and 60% less insulin requirement over three hours after ingesting a glucose drink.

The new approach of keeping the soleus muscle metabolism humming is also effective at doubling the normal rate of fat metabolism in the fasting period between meals, reducing the levels of fat in the blood (VLDL triglyceride).

Marc Hamilton, professor of Health and Human Performance at the University of Houston. Credit: University of Houston

Additional publications are in the works focused on how to instruct people to properly learn this singular movement, but without the sophisticated laboratory equipment used in this latest study.

This is not some new fitness tip or diet of the month, the scientists are quick to point out. It’s a potent physiological movement that capitalizes on the unique features of the soleus.

Potential first step toward a healthcare breakthrough

Hamilton calls it the “most important study” ever completed at his Metabolic Innovations lab at UH and said the discovery could be a solution to a variety of health problems caused by spending hours each day living with muscle metabolism that is too low, caused by inactivity. The average American sits about 10 hours a day.

Metabolic Innovations Lab

Marc Hamilton, professor of Health and Human Performance at the University of Houston is pioneering the “soleus pushup” which effectively elevates muscle metabolism for hours, even while sitting. Credit: University of Houston

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Regardless of a person’s level of physical activity, too much sitting has been shown to increase the risk of heart disease, diabetes, dementia, and more. Over half of all American adults, and 80% of people over 65, are living with metabolic problems caused by either diabetes or prediabetes.

Having a low metabolic rate while seated is especially troublesome for people who are at high risk for age-associated metabolic diseases such as metabolic syndrome and type 2 diabetes.

Hamilton said inactive muscles require less energy than most people seem to understand, saying it’s “one of the most fundamental, yet overlooked issues” guiding the way toward discovering metabolic solutions to assist in preventing some age-associated chronic diseases.

Deborah Hamilton, Marc Hamilton, and Theodore Zderic

Study authors pictured left to right: Deborah Hamilton, senior research manager; Marc Hamilton, professor; and Theodore Zderic, research assistant professor. Credit: University of Houston

“All of the 600 muscles combined normally contribute only about 15% of the whole-body oxidative metabolism in the three hours after ingesting carbohydrates. Despite the fact that the soleus is only 1% of the body weight, it is capable of raising its metabolic rate during SPU contractions to easily double, even sometimes triple, the whole-body carbohydrate oxidation.

We are unaware of any existing or promising pharmaceuticals that come close to raising and sustaining whole-body oxidative metabolism at this magnitude.”

Reference: “A potent physiological method to magnify and sustain soleus oxidative metabolism improves glucose and lipid regulation” by Marc T. Hamilton, Deborah G.Hamilton and Theodore W. Zderic, 5 August 2022, iScience.
DOI: 10.1016/j.isci.2022.104869

Source: SciTechDaily