Soumya Kannan is a 2021-22 Yang-Tan Center for Molecular Therapeutics Graduate Student Fellow in the lab of MIT Professor Feng Zhang and co-first author with…
Posts published in “CRISPR”
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Researchers Engineer a Mini CRISPR Genetic Editing System That Could Be Easier To Deliver Into Cells
Researchers Engineer a Mini CRISPR Genetic Editing System That Could Be Easier To Deliver Into Cells
CRISPR illustration. Credit: National Institutes of Health A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because…
An illustration by study coauthor Stephanie Gamez depicts flightless females and sterile male mosquitoes, features of the new precision-guided sterile insect technique, or pgSIT, which…
Stanford researchers have engineered a new miniature CRISPR system that should be easier to deliver into human cells. Bioengineers have repurposed a “non-working” CRISPR system…
The reactions involved in the FIND-IT assay to detect infection with the SARS-CoV-2 virus. When the Cas13 enzyme (left) binds to its target RNA, it…
First successful use aboard International Space Station of new technique for studying DNA repair in yeast. Researchers have developed and successfully demonstrated a novel method…
CRISPR illustration. Credit: National Institutes of Health Multiplexed gene activation system allows for four to six times the activation capacity of current CRISPR technology, with…
Staining for RAD51 (bright cyan-colored dot) in a fertilized one-cell mouse embryo shows repair of a CRISPR-induced DNA break. Credit: Image courtesy of the researchers.…
The MIT spinout KSQ Therapeutics uses large scale gene editing to study the role of genes in diseases like cancer. Credit: courtesy of KSQ Therapeutics…
Electron microscopy image of DNA origami rotor arms, which are the faint orange “L’s” attached to the purple tracking particles. Credit: Image courtesy of Julene…
Phylogenetic trees, starting with an individual cancer cell. Each color represents a different location in the body. A very colorful tree shows a highly metastatic…
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic…
A new CRISPR-based test for COVID-19 developed by researchers at Gladstone Institutes, UC Berkeley, and UC San Francisco essentially converts a smartphone camera into a…
Shedding light on human brain development. Credit: ©Dexheimer/IMBA Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called…
This scanning electron microscope image shows SARS-CoV-2 (round gold objects) emerging from the surface of cells cultured in the lab. Credit: NIAID-RML A CRISPR-based test…
The development of mRNA knock-down technologies for use in vertebrate organisms such as zebrafish has been limited. CRISPR-RfxCas13d has been identified as an effective method…
The 3D structure of a base editor, comprised of the Cas9 protein (white and gray), which binds to a DNA target (teal and blue helix)…
Cosmo, a 110-pound bull calf was born in April of 2020 at UC Davis. Scientists successfully genome-edited him as an embryo to produce more male…
Gene editing Cas9 protein. Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences. In nature, bacteria use CRISPR as an…
When three specific genetic mutations are combined and tuned just right, scientists can turn tomato plants into extremely compact bushes ideal for urban agriculture. Just…