Enveloped viruses get their outer coat by budding from cells they’ve invaded. CRISPR-Cas9 researchers coopted this behavior to produce envelope-derived vehicles that encapsulate Cas9 proteins…
Posts published in “CRISPR”
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An artistic rendering of CRISPR-enhanced T-cells attacking a tumor. Research has shown that the gene-editing system CRISPR can modulate T-cell behavior to make them better…
Scientists have discovered that CRISPR-Cas9 gene editing can cause leukemia-derived cancer cells to eliminate important genes under stress. This overlooked phenomenon affects gene regulation and…
NICER, a new gene editing method developed by Japanese researchers, presents a safer alternative to CRISPR/Cas9 by significantly reducing unintended DNA mutations, enhancing genetic disease…
Using the novel algorithm FLSHclust, researchers have identified 188 rare and previously unknown CRISPR-linked gene modules, including a groundbreaking type VII CRISPR-Cas system. This discovery,…
Researchers at MIT, the Broad Institute, and the National Institutes of Health have developed a new search algorithm that has identified 188 kinds of new…
Scientists at Oak Ridge National Laboratory have advanced CRISPR Cas9 technology for microbial genome editing by using quantum biology and explainable artificial intelligence. This breakthrough…
Proteins in human cells commonly undergo N-terminal acetylation, a modification by the enzyme group N-terminal acetyltransferases (NATs), the function of which has been largely mysterious.…
For millennia, evolution naturally mutated tomatoes, with humans later selecting preferred traits. Now, CRISPR genome editing allows even more precise changes. Researchers at Cold Spring…
Scientists have detailed the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems, CRISPR-Cas13bt3, used for RNA modification, which operates differently from other proteins…
Alan Baik is part of the team in Isha Jain’s lab at Gladstone Institutes that uncovered why high levels of oxygen can cause lasting problems…
In a new opinion paper published in Trends in Genetics, evolutionary geneticist Asher Cutter highlights the ethical and scientific considerations surrounding “genetic welding,” the use…
Proteins that glow bright blue or green, as pictured here, could make disease diagnosis quicker and easier. Credit: Maarten Merkx Although there have been significant…
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene editing technology that allows scientists to make precise changes to the DNA of living…
Researchers at Brigham and Women’s Hospital have found a way to use cancer cells to fight cancer. In a study published in Science Translational Medicine,…
Cornell University researchers have revealed how a key mechanism in genes is controlled. Cornell University researchers have discovered a crucial mechanism in how genes are…
The researchers believe that their method will also be effective in discovering genetic factors necessary for the generation of rose flavor by yeast in alcoholic…
Although CRISPR therapeutics are incredibly effective, the researchers warn that they could promote cancer. The study showed that CRISPR therapeutics can damage the genome. The…
Restorative gene editing using sequences from the counterpart chromosome: The standard CRISPR enzyme Cas9 offers the ability to make repairs but also potentially results in…
The injection causes type B white blood cells to be genetically engineered inside the patient’s body that would generate neutralizing antibodies against the HIV virus.…